Original Article

Altered Immune Response to Decellularized Porcine Small Intestinal Sub-Mucosa (DPSIS) Graft in Dogs Suffering from Keratoconjunctivitis Sicca

Year: 2021 | Month: April | Volume 11 | Issue 2

References (24)

Amouzegar, A., Chauhan, S.K. and Dana, R. 2016. Alloimmunity and tolerance in corneal transplantation. J. Immunol., 196: 3983–3991.

View at Google Scholar

Bustin, S.A. 2002. Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. J. Mol. Endocrinol., 29: 23-39.

View at Google Scholar

Chelladuraai, S., Singh, K., Gopinathan, A. and Agrawal R. K. 2019. Evaluation of three different impression cytology techniques for RNA retrieval from canine ocular surface epithelial cells. Res. J. Biotechnol., 14(10): 2278-4535

View at Google Scholar

El Annan, J., Goyal, S., Zhang, Q., Freeman, G.J., Sharpe, A.H. and Dana, R. 2010. Regulation of T-cell chemotaxis by programmed death-ligand 1 (PD-L1) in dry eye-associated corneal inflammation. Invest. Ophthalmol. Vis. Sci., 51: 3418-3423.

View at Google Scholar

Featherstone, H.J., Sansom, J. and Heinrich, C.L. 2001. The use of porcine small intestinal submucosa in ten cases of feline corneal disease. Vet. Ophthalmol., 4: 147-153.

View at Google Scholar

Goulle, F. 2012. Use of porcine small intestinal submucosa for corneal reconstruction in dogs and cats: 106 cases. J. Small Anim. Pract., 53: 34–43.

View at Google Scholar

Hori, J., Joyce, N.C. and Streilein, J.W. 2000. Immune privilege and immunogenicity reside among different layers of the mouse cornea. Invest. Ophthalmol. Vis. Sci., 41: 3032-3042.

View at Google Scholar

Hori, J., Wang, M., Miyashita, M., Tanemoto, K., Takahashi, H., Takemori, T., Okumura, K., Yagita, H. and Azumae, M. 2006. B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts. J. Immunol., 177: 5928-5935.

View at Google Scholar

John C., Gopinathan A., Singh, K., Sharma, P., Sowbharenya, C. and Sarangom, S.B. 2018. Clinical evaluation of topical tacrolimus ointment usage in different stages of keratoconjunctivitis sicca in dogs. Turk. J. Vet. Anim. Sci., 42: 259-268.

View at Google Scholar

John, C., Gopinathan, A., Singh, K., Sharma, P., Sowbharenya, C. and Sarangom, S.B. 2018. Clinical evaluation of topical tacrolimus ointment usage in different stages of keratoconjunctivitis sicca in dogs. Turk. J. Vet. Anim. Sci., 42: 259-268.

View at Google Scholar

John, C., Gopinathan, A., Singh, K., Sowbharenya, C., Kumar, N., Sahoo, M., and Agrawal, R.K. 2020. Conjunctival Immunocytochemistry with Interferon Gamma and Caspase 3 for Clinical Staging of Keratoconjunctivitis Sicca (KCS) in Dogs. Int. J. Curr. Microbiol. App. Sci. 9: 2952-2961

View at Google Scholar

Kobayashi, M., Kawano, S., Hatachi, S., Kurimoto, C., Okazaki, T., Iwai, Y., Honjo, T., Tanaka, Y., Minato, N., Komori, T., Maeda, S. and Kumagai, S. 2005. Enhanced expression of programmed death-1 (PD-1)/PD-L1 in salivary glands of patients with Sjögren’s syndrome. J. Rheumatol., 32: 2156– 2163.

View at Google Scholar

Kong, L., Ogawa, N., Nakabayashi, T., Liu, G.T., D’Souza, E., McGuff, H.S., Guerrero, D., Talal, N. and Dang, H. 1997. Fas and Fas ligand expression in the salivary glands of patients with primary Sjögren’s syndrome. Arthritis Rheum., 40: 87– 97.

View at Google Scholar

Kropp, B.P. and Cheng, E.Y. 2000. Bioengineering organs using small intestinal submucosa scaffolds: in-vivo tissueengineering technology. J. Endourol., 14: 59-62.

View at Google Scholar

Kumar, A., Gopinathan, A., Singh, K., Sasikala, R. and Swapana, C.R. 2020. Effect of tacrolimus treatment on tear fluid cytokines of Keratoconjunctivitis sicca affected dogs. Int. J. Curr. Microbiol. App. Sci., 9(9): 3347-3356.

View at Google Scholar

Moore, P.A. 2003. Diagnosis and management of chronic corneal epithelial defects (Indolent corneal ulcerations). Clin. Tech. Small Anim. Pract., 18: 168-177.

View at Google Scholar

Morita, M., Fujita, N., Takahashi, A., Nam, E.R., Yui, S., Chung, C.S., Kawahara, N., Lin, H.Y., Tsuzuki, K., Nakagawa, T. and Nishimura, R. 2015. Evaluation of ABCG2 and p63 expression in canine cornea and cultivated corneal epithelial cells. Vet. Ophthalmol., 18: 59–68.

View at Google Scholar

Sangeetha, P., Maiti, S., Sharma, N.K., Singh, K., Gopinathan, A., Ninu, A., Remya, V., Sivanarayanan, T., Mohsina, A., Mohan, D. and Mahan, P.T. 2016. Development of bioengineered corneal matrix for reconstructive surgery of eye. Trends Biomater. Artif. Organs., 30: 85-89.

View at Google Scholar

Shen, L., Jin, Y., Freeman, G.J., Sharpe, A.H. and Dana, M.R. 2007. The function of donor versus recipient programmed death-ligand 1 in corneal allograft survival. J. Immunol., 179: 3672-3679.

View at Google Scholar

Singh, K., Gopinathan, A., Sangeetha, P., Kumar, N. and Singh, K.P. 2016. Development and clinical application of decellularized porcine SIS and cornea for the repair of corneal defects in animals. Indian J. Anim. Sci., 86: 1391–1395.

View at Google Scholar

Singh, K., Gopinathan, A., Sangeetha, P., Kumar, N. and Singh, K.P. 2016. Development and clinical application of decellularized porcine SIS and cornea for the repair of corneal defects in animals. Indian J. Anim. Sci., 86: 1391–1395.

View at Google Scholar

Sowbharenya, C., Singh, K., Gopinathan, A. and Sarangom, S.B. 2019. Decellularized porcine small intestinal submucosa for the repair of deep corneal ulcer in dogs. Int. J. Adv. Res. Biol. Sci., 9: 14-18.

View at Google Scholar

Swapana, C.R., Gopinathan, A., Singh, K., Sasikala, R., Kumar, A., Chelladuraai, S., Kumar, N., Sahoo, M. and Agrawal, R.K. 2020. Down-regulation of rho GTPase-activating protein 7 (DLC1) in tear film and modulation of rho GTPase dynamics by Rosuvastatin in dogs suffering from keratoconjunctivitis sicca. J. Anim. Res., 10(6): 889-898.

View at Google Scholar

Turner, H.C., Budak, M.T., Akinci, M.A. and Wolosin, J.M. 2007. Comparative analysis of human conjunctival and corneal epithelial gene expression with oligonucleotide microarrays. Invest. Ophthalmol. Vis. Sci., 48: 2050-2061.

View at Google Scholar

Economic Affairs, Quarterly Journal of Economics| In Association with AESSRA

75643578 - Visitors since February 20, 2019